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Pomalidomide-PEG3-C2-NH2 (TFA)

Name: Pomalidomide-PEG3-C2-NH2 (TFA)
Brand: TargetMol
SKU: T17882
Price: 50 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T17882

Alias Pomalidomide-PEG3-C2-NH2 (TFA) (2093416-31-8 free base), E3 ligase Ligand-Linker Conjugates 30 (TFA), Cereblon Ligand-Linker Conjugates 5 (TFA)

Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

Pomalidomide-PEG3-C2-NH2 (TFA)

😃Good

Catalog No. T17882Alias Pomalidomide-PEG3-C2-NH2 (TFA) (2093416-31-8 free base), E3 ligase Ligand-Linker Conjugates 30 (TFA), Cereblon Ligand-Linker Conjugates 5 (TFA)

Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

Pack Size	Price	Availability	Quantity
100 mg	Inquiry	Backorder
500 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description	Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
Alias	Pomalidomide-PEG3-C2-NH2 (TFA) (2093416-31-8 free base), E3 ligase Ligand-Linker Conjugates 30 (TFA), Cereblon Ligand-Linker Conjugates 5 (TFA)

Chemical Properties

Molecular Weight	562.49
Formula	C₂₃H₂₉F₃N₄O₉
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 16.67 mg/mL (29.64 mM), Sonication is recommended.

DMSO: 100 mg/mL (177.78 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7778 mL	8.8890 mL	17.7781 mL	88.8905 mL
5 mM	0.3556 mL	1.7778 mL	3.5556 mL	17.7781 mL
10 mM	0.1778 mL	0.8889 mL	1.7778 mL	8.8890 mL
20 mM	0.0889 mL	0.4445 mL	0.8889 mL	4.4445 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0356 mL	0.1778 mL	0.3556 mL	1.7778 mL
100 mM	0.0178 mL	0.0889 mL	0.1778 mL	0.8889 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Pomalidomide-PEG-3-C2-NH2 (TFA)Pomalidomide PEG3 C2 NH2 (TFA)2093416-31-8 free base2093416-31-8Pomalidomide-PEG3-C2-NH2 (TFA)Cereblon Ligand-Linker Conjugates 5Pomalidomide-PEG3-C2-NH2E3 ligase Ligand-Linker Conjugates 30PomalidomidePEG3C2NH2 (TFA)

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