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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Propargyl-PEG3-sulfone-PEG3-propargyl is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. |
In vitro | PROTACs comprise two ligands connected by a linker: one binds to an E3 ubiquitin ligase, while the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 494.6 |
Formula | C22H38O10S |
Cas No. | 2055024-44-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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