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Propofol β-D-Glucuronide

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Catalog No. T37378Cas No. 114991-26-3

Propofol β-D-glucuronide is a metabolite of propofol sulfate, a short-acting anesthetic agent. The metabolite is generated through the glucuronidation of propofol by uridine diphosphate glucuronosyltransferases, and propofol metabolism appears to occur more rapidly in women than in men. [1] [2]

Propofol β-D-Glucuronide

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Catalog No. T37378Cas No. 114991-26-3

Pack Size	Price	Availability
500 μg	$78	35 days
1 mg	$143	35 days
5 mg	$523	35 days
10 mg	$990	35 days

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	354.39
Formula	C₁₈H₂₆O₇
Cas No.	114991-26-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 30 mg/mL (84.65 mM), Sonication is recommended.

DMF: 30 mg/mL (84.65 mM), Sonication is recommended.

Ethanol: 30 mg/mL (84.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO/DMF/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.8218 mL	14.1088 mL	28.2175 mL	141.0875 mL
5 mM	0.5644 mL	2.8218 mL	5.6435 mL	28.2175 mL
10 mM	0.2822 mL	1.4109 mL	2.8218 mL	14.1088 mL
20 mM	0.1411 mL	0.7054 mL	1.4109 mL	7.0544 mL
50 mM	0.0564 mL	0.2822 mL	0.5644 mL	2.8218 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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