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Propynyl-PEG1-Ac, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Propynyl-PEG1-Ac, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are composed of two ligands linked together: one binds to an E3 ubiquitin ligase, and the other to the target protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | Propynyl-PEG1-Ac |
Molecular Weight | 158.15 |
Formula | C7H10O4 |
Cas No. | 944561-45-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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