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PROTAC BCR-ABL1 ligand 1

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Catalog No. T73941Cas No. 2489876-34-6

GMB-475, also known as PROTAC BCR-ABL1 ligand 1, allosterically targets and binds to the BCR-ABL1 protein. It effectively recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation of BCR-ABL1 [1].

PROTAC BCR-ABL1 ligand 1

PROTAC BCR-ABL1 ligand 1

😃Good
Catalog No. T73941Cas No. 2489876-34-6
GMB-475, also known as PROTAC BCR-ABL1 ligand 1, allosterically targets and binds to the BCR-ABL1 protein. It effectively recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation of BCR-ABL1 [1].
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Product Introduction

Bioactivity
Description
GMB-475, also known as PROTAC BCR-ABL1 ligand 1, allosterically targets and binds to the BCR-ABL1 protein. It effectively recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation of BCR-ABL1 [1].
Chemical Properties
Molecular Weight347.29
FormulaC17H12F3N3O2
Cas No.2489876-34-6
Relative Density.1.411 g/cm3 (Predicted)
Storage & Solubility Information
StorageShipping with blue ice.

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