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Protizinic acid inhibits phospholipase A2 (PLA2) with an IC 50 of 210 μM. Protizinic acid has antiinflammatory and antipyretic activity which is an orally active non-steroidal antiinflammatory agent [1] [2].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Protizinic acid inhibits phospholipase A2 (PLA2) with an IC 50 of 210 μM. Protizinic acid has antiinflammatory and antipyretic activity which is an orally active non-steroidal antiinflammatory agent [1] [2]. |
In vitro | Protizinic acid both inhibits the in vitro production of leukokinin and acts antagonistically towards it at its receptor site [1]. |
In vivo | Utilizing an in vivo leukokinin (LK) generation system in a feline acute ischemia model, the administration of 3 mg/kg Protizinic acid via intravenous injection twice to cats experiencing acute cardiac ischemia inhibits increased blood acid protease activity and significantly prevents the reduction of leukokininogen, leukokinin's precursor [1]. Furthermore, the oral intake of 30 mg/kg Protizinic acid markedly reduces arachidonic acid-induced erythema in guinea pigs [2]. |
Molecular Weight | 315.39 |
Formula | C17H17NO3S |
Cas No. | 13799-03-6 |
Storage | Shipping with blue ice. |
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