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PSB 1114

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Catalog No. T23200

PSB 1114 is an effective and selective agonist of the P2Y2 receptor (EC50: 0.134 μM).

PSB 1114

PSB 1114

😃Good
Catalog No. T23200
PSB 1114 is an effective and selective agonist of the P2Y2 receptor (EC50: 0.134 μM).
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Product Introduction

Bioactivity
Description
PSB 1114 is an effective and selective agonist of the P2Y2 receptor (EC50: 0.134 μM).
In vitro
PSB 1114 activated P2Y2, P2Y4, and P2Y6 (EC50: 0.134, 9.3 and 7.0 μM respectively). It exhibited >60-fold selectivity versus P2Y6 and P2Y4 receptors [1].
Chemical Properties
Molecular Weight622.14
FormulaC10H11F2N2Na4O13P3S
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: <10 mM
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.6074 mL8.0368 mL16.0736 mL80.3678 mL
5 mM0.3215 mL1.6074 mL3.2147 mL16.0736 mL
10 mM0.1607 mL0.8037 mL1.6074 mL8.0368 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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