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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Pyrene-amido-PEG4-CH2CH2COOH is a polyethylene glycol (PEG) derived linker specifically designed for constructing proteolysis targeting chimeras (PROTACs)[1]. |
In vitro | PROTACs consist of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, while the other binds to the target protein. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 495.56 |
Formula | C28H33NO7 |
Cas No. | 1817735-34-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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