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R-84760 hydrochloride
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Catalog No. T28495Cas No. 157824-23-2
Alias R-86436 hydrochloride, R86436 hydrochloride, R84760 hydrochloride, R 86436 hydrochloride, R 84760 hydrochloride
R-84760 is a κ-opioid receptor agonist. R-84760 produces an extremely potent antinociceptive effect against tonic pain through the kappa-opioid receptors; the sites of action of subcutaneously administered R-84760 are the supraspinal and spinal loci in the central nervous system; and a part of the mechanism of the antinociceptive effect of R-84760 is activation of the descending noradrenergic pathway.
R-84760 hydrochloride
😃Good
Catalog No. T28495Alias R-86436 hydrochloride, R86436 hydrochloride, R84760 hydrochloride, R 86436 hydrochloride, R 84760 hydrochlorideCas No. 157824-23-2
R-84760 is a κ-opioid receptor agonist. R-84760 produces an extremely potent antinociceptive effect against tonic pain through the kappa-opioid receptors; the sites of action of subcutaneously administered R-84760 are the supraspinal and spinal loci in the central nervous system; and a part of the mechanism of the antinociceptive effect of R-84760 is activation of the descending noradrenergic pathway.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,820 | 8-10 weeks | |
| 50 mg | $2,380 | 8-10 weeks | |
| 100 mg | $3,100 | 8-10 weeks |
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Bioactivity
Chemical Properties
| Description | R-84760 is a κ-opioid receptor agonist. R-84760 produces an extremely potent antinociceptive effect against tonic pain through the kappa-opioid receptors; the sites of action of subcutaneously administered R-84760 are the supraspinal and spinal loci in th |
| Alias | R-86436 hydrochloride, R86436 hydrochloride, R84760 hydrochloride, R 86436 hydrochloride, R 84760 hydrochloride |
| Molecular Weight | 435.84 |
| Formula | C19H25Cl3N2OS |
| Cas No. | 157824-23-2 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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