Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1].
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | $ 1,160.00 |
Description | RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1]. |
In vitro | RAS/RAS-RAF-IN-1 (compound 89; for 4 hours) has an EC50 of 0.5 μμ-5.0 μμ for BRAF-GTP-KRAS-G12C disruption and has an IC50 of 1.0 μμ-10 μμ for pERK inhibition in H358 cells[1]. |
Molecular Weight | 807.993 |
Formula | C45H57N7O7 |
CAS No. | 2447039-81-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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RAS/RAS-RAF-IN-1 2447039-81-6 RAS/RAS RAF IN 1 RAS/RASRAFIN1 inhibitor inhibit