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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $1,160 | Backorder |
Description | RAS/RAS-RAF-IN-1 is a potent inhibitor of RAS and RAS-RAF, exhibiting a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity and demonstrating antitumor activity[1]. |
In vitro | RAS/RAS-RAF-IN-1 (compound 89; for 4 hours) exhibits an EC50 of 0.5 μμ-5.0 μμ for BRAF-GTP-KRAS-G12C disruption and an IC50 of 1.0 μμ-10 μμ for pERK inhibition in H358 cells[1]. |
Molecular Weight | 807.993 |
Formula | C45H57N7O7 |
Cas No. | 2447039-81-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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