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Resolvin D3 (RvD3), originating from docosahexaenoic acid (DHA), is a dysregulated mediator that plays a crucial role in reducing arthritic inflammation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 μg | 363 € | 35 days | |
25 μg | 841 € | 35 days | |
50 μg | 1.624 € | 35 days | |
100 μg | 2.840 € | 35 days |
Description | Resolvin D3 (RvD3), originating from docosahexaenoic acid (DHA), is a dysregulated mediator that plays a crucial role in reducing arthritic inflammation. |
In vitro | RvD3 (RvD3; 10 nM) effectively suppresses the activation of NF-κB induced by tumor necrosis factor-α in A549 epithelial cells[2]. |
In vivo | Resolvin D3 (RvD3; 100 ng/100 μl; IP; daily for 6 days) effectively mitigates arthritis progression, reduces edema, and curtails leukocyte accumulation in murine K/BxN-serum induced arthritis in both male C57Bl/6 mice (12 weeks old) and ALX/fpr2/3 KO mice. |
Alias | RvD3 |
Molecular Weight | 376.493 |
Formula | C22H32O5 |
Cas No. | 916888-47-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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