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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $498 | 10-14 weeks | |
100 mg | $769 | 10-14 weeks |
Description | Revizinone, a novel selective phosphodiesterase inhibitor, exhibits an IC50 value of 0.036 microM on this enzyme. |
In vitro | Revizinone significantly increased global LV function and systolic wall thickening in ischemic areas at doses greater than or equal to 0.16 mg/kg i.v. The administration of Revizinone improved the hemodynamic profile with an increase in cardiac output, a decrease in systemic vascular resistance, and a stable heart rate and mean arterial blood pressure. With regard to the reconstitution of contractility and cardiac function Revizinone (E-isomer) was 10 fold more potent than R 79595 and nearly 100 fold more potent than R 80123 (Z-isomer) [1] [2][4]. |
Alias | R80122 |
Molecular Weight | 459.54 |
Formula | C26H29N5O3 |
Cas No. | 133718-29-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||
Solubility Information | DMSO: 4.6 mg/mL (10.01 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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