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RMC-5552

Name: RMC-5552
Brand: TargetMol
SKU: T36089
Rating: 4.5 (1 reviews)

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Catalog No. T36089Cas No. 2382768-62-7

RMC-5552 is a potent and selective mTORC1 inhibitor, effectively inhibiting phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively [RMC-5552]. The compound exhibits significant anti-cancer activity.

RMC-5552

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Catalog No. T36089Cas No. 2382768-62-7

Pack Size	Price	Availability	Quantity
2 mg	$782	7-10 days

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Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	1778.157
Formula	C₉₃H₁₃₆N₁₀O₂₄
Cas No.	2382768-62-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 166.67 mg/mL (93.73 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.5624 mL	2.8119 mL	5.6238 mL	28.1190 mL
5 mM	0.1125 mL	0.5624 mL	1.1248 mL	5.6238 mL
10 mM	0.0562 mL	0.2812 mL	0.5624 mL	2.8119 mL
20 mM	0.0281 mL	0.1406 mL	0.2812 mL	1.4060 mL
50 mM	0.0112 mL	0.0562 mL	0.1125 mL	0.5624 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

RMC5552RMC-5552RMC 5552