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RMS-07

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Catalog No. T73483Cas No. 2645409-78-3

RMS-07, a covalent inhibitor of Monopolar Spindle Kinase 1 (MPS1/TTK), exhibits a potent inhibitory concentration (IC50) of 13.1 nM. Specifically, it targets a poorly conserved cysteine located in the hinge region of the kinase.

RMS-07

RMS-07

😃Good
Catalog No. T73483Cas No. 2645409-78-3
RMS-07, a covalent inhibitor of Monopolar Spindle Kinase 1 (MPS1/TTK), exhibits a potent inhibitory concentration (IC50) of 13.1 nM. Specifically, it targets a poorly conserved cysteine located in the hinge region of the kinase.
Pack SizePriceAvailabilityQuantity
25 mg$2,42010-14 weeks
50 mg$3,18010-14 weeks
100 mg$4,30010-14 weeks
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Product Introduction

Bioactivity
Description
RMS-07, a covalent inhibitor of Monopolar Spindle Kinase 1 (MPS1/TTK), exhibits a potent inhibitory concentration (IC50) of 13.1 nM. Specifically, it targets a poorly conserved cysteine located in the hinge region of the kinase.
Chemical Properties
Molecular Weight604.74
FormulaC35H40N8O2
Cas No.2645409-78-3
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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