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RO2443

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Catalog No. T70726Cas No. 1416663-79-0

RO2443 is a dual inhibitor of the MDM2-p53 or MDMX-p53 protein-protein interaction, inducung MDM2 and MDMX dimerization and activating the p53 pathway.

RO2443

RO2443

😃Good
Catalog No. T70726Cas No. 1416663-79-0
RO2443 is a dual inhibitor of the MDM2-p53 or MDMX-p53 protein-protein interaction, inducung MDM2 and MDMX dimerization and activating the p53 pathway.
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
RO2443 is a dual inhibitor of the MDM2-p53 or MDMX-p53 protein-protein interaction, inducung MDM2 and MDMX dimerization and activating the p53 pathway.
Chemical Properties
Molecular Weight401.79
FormulaC20H14ClF2N3O2
Cas No.1416663-79-0
Storage & Solubility Information
StorageShipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LY 297802NNC11 1053RO-2443RO2443RO 2443NNC111053NNC11-1053LY297802LY-297802
Related Tags: buy RO2443 | purchase RO2443 | RO2443 cost | order RO2443 | RO2443 chemical structure | RO2443 formula | RO2443 molecular weight
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