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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $995 | Backorder |
Description | ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s), effectively targeting hGX with an IC50 of 80 nM. It efficiently inhibits the phosphorylation of ERK1/2 and p-38. sPLA2s, belonging to the disulfide-rich, Ca2+-dependent enzyme family, catalyze the hydrolysis of glycero-phospholipids at the sn-2 position, resulting in the release of a fatty acid and a lysophospholipid. ROC-0929 holds promise in researching inflammation-related diseases. |
Molecular Weight | 561.65 |
Formula | C30H31N3O6S |
Cas No. | 1048660-43-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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