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S 0960

Name: S 0960
Brand: TargetMol
SKU: T70688
Price: 758 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T70688Cas No. 142974-51-4

Alias S0960

S 0960 is a dimeric bile acid analog, a specific inhibitor of the sodium-dependent bile salt transporter in the ileum, used in metabolic disease research.

S 0960

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Purity: 100%

Catalog No. T70688Alias S0960Cas No. 142974-51-4

S 0960 is a dimeric bile acid analog, a specific inhibitor of the sodium-dependent bile salt transporter in the ileum, used in metabolic disease research.

Pack Size	Price	Availability
1 mg	$758	In Stock
5 mg	$1,580	In Stock
10 mg	$2,130	In Stock
25 mg	$3,170	In Stock
50 mg	$4,180	In Stock

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Purity:100%

ee:100%

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COA CSFC HNMR HPLC LCMS ORP

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	S 0960 is a dimeric bile acid analog, a specific inhibitor of the sodium-dependent bile salt transporter in the ileum, used in metabolic disease research.
Targets&IC50	ASBT:5.8 μM
In vitro	S 0960 is a specific inhibitor of sodium-dependent bile salt transporter (ASBT) with an IC50 of 5.8 μmol/L. [1]
In vivo	S 0960 (10 mg/kg) was injected intravenously to affect H-taurocholate reabsorption in rats. [1]
Alias	S0960

Chemical Properties

Molecular Weight	798.14
Formula	C₄₈H₇₉NO₈
Cas No.	142974-51-4
Smiles	O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@@H](NC(CC[C@@H](C)[C@@]5([C@]6(C)[C@@](CC5)([C@]7([C@](C[C@@H]6O)([C@]8(C)[C@](C[C@H]7O)(C[C@H](O)CC8)[H])[H])[H])[H])[H])=O)CC4)[H])[H])[H])[H]

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

UAWJ-246UAWJ 246S-0960S 0960