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Sacibertinib

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Catalog No. T64225Cas No. 1351941-69-9

Sacibertinib is a tyrosine kinase (Trk) inhibitor with activity against EGFR-TK phosphorylation (EC50: 110 nM) and HER2 (EC50: 244 nM), demonstrating antitumor effects.

Sacibertinib

Sacibertinib

😃Good
Catalog No. T64225Cas No. 1351941-69-9
Sacibertinib is a tyrosine kinase (Trk) inhibitor with activity against EGFR-TK phosphorylation (EC50: 110 nM) and HER2 (EC50: 244 nM), demonstrating antitumor effects.
Pack SizePriceAvailabilityQuantity
25 mg$2,14010-14 weeks
50 mg$2,78510-14 weeks
100 mg$3,52010-14 weeks
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Product Introduction

Bioactivity
Description
Sacibertinib is a tyrosine kinase (Trk) inhibitor with activity against EGFR-TK phosphorylation (EC50: 110 nM) and HER2 (EC50: 244 nM), demonstrating antitumor effects.
Chemical Properties
Molecular Weight599.08
FormulaC32H31ClN6O4
Cas No.1351941-69-9
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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