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SAHA chloroalkane T1

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Catalog No. T19556Cas No. 1613617-05-2

SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1.

SAHA chloroalkane T1

SAHA chloroalkane T1

😃Good
Catalog No. T19556Cas No. 1613617-05-2
SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1.
Pack SizePriceAvailabilityQuantity
25 mg$6886-8 weeks
50 mg$9136-8 weeks
100 mg$1,5306-8 weeks
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Product Introduction

Bioactivity
Description
SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1.
In vitro
in K-562 cells,SAHA chloroalkane T1 minimally affects SAHA potency, allowing binding interactions with the targets to occur under conditions relevant to the desired cellular phenotype.
Chemical Properties
Molecular Weight719.26
FormulaC33H55ClN4O11
Cas No.1613617-05-2
Relative Density.1.199 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 125 mg/mL (173.79 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3903 mL6.9516 mL13.9032 mL69.5159 mL
5 mM0.2781 mL1.3903 mL2.7806 mL13.9032 mL
10 mM0.1390 mL0.6952 mL1.3903 mL6.9516 mL
20 mM0.0695 mL0.3476 mL0.6952 mL3.4758 mL
50 mM0.0278 mL0.1390 mL0.2781 mL1.3903 mL
100 mM0.0139 mL0.0695 mL0.1390 mL0.6952 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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