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SAHA chloroalkane T1

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SAHA chloroalkane T1

Catalog No. T19556Cas No. 1613617-05-2

SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1.

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Pack Size	Price	Availability
25 mg	$688	6-8 weeks
50 mg	$913	6-8 weeks
100 mg	$1,530	6-8 weeks

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Product Introduction

Bioactivity

Description	SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1.
In vitro	in K-562 cells,SAHA chloroalkane T1 minimally affects SAHA potency, allowing binding interactions with the targets to occur under conditions relevant to the desired cellular phenotype.

Chemical Properties

Molecular Weight	719.26
Formula	C33H55ClN4O11
Cas No.	1613617-05-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 125 mg/mL (173.79 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3903 mL	6.9516 mL	13.9032 mL	69.5159 mL
5 mM	0.2781 mL	1.3903 mL	2.7806 mL	13.9032 mL
10 mM	0.1390 mL	0.6952 mL	1.3903 mL	6.9516 mL
20 mM	0.0695 mL	0.3476 mL	0.6952 mL	3.4758 mL
50 mM	0.0278 mL	0.1390 mL	0.2781 mL	1.3903 mL
100 mM	0.0139 mL	0.0695 mL	0.1390 mL	0.6952 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SAHA chloroalkane T-1SAHA chloroalkane T1