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Sapropterin free base

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Catalog No. T21366Cas No. 62989-33-7
Alias THB, Tetrahydro-6-biopterin, Phenoptin, Dapropterin, BPH4, 6R-BH4

Sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of dopamine, epinephrine, melatonin, norepinephrine, neurotransmitters 5-HT, it is also a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.

Sapropterin free base

Sapropterin free base

😃Good
Catalog No. T21366Alias THB, Tetrahydro-6-biopterin, Phenoptin, Dapropterin, BPH4, 6R-BH4Cas No. 62989-33-7
Sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of dopamine, epinephrine, melatonin, norepinephrine, neurotransmitters 5-HT, it is also a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.
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Product Introduction

Bioactivity
Description
Sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of dopamine, epinephrine, melatonin, norepinephrine, neurotransmitter
AliasTHB, Tetrahydro-6-biopterin, Phenoptin, Dapropterin, BPH4, 6R-BH4
Chemical Properties
Molecular Weight241.25
FormulaC9H15N5O3
Cas No.62989-33-7
Relative Density.1.89g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: Insoluble
DMSO: Soluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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