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Saredutant

Name: Saredutant
Brand: TargetMol
SKU: T16842
Price: 293 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T16842Cas No. 142001-63-6

Alias SR 48968C, SR 48968

Saredutant is an antagonist of selective NK2 receptors.

Saredutant

😃Good

Catalog No. T16842Alias SR 48968C, SR 48968Cas No. 142001-63-6

Saredutant is an antagonist of selective NK2 receptors.

Pack Size	Price	Availability
2 mg	$242	5 days
5 mg	$297	5 days
25 mg	$987	8-10 weeks
50 mg	$1,360	8-10 weeks
100 mg	$1,860	8-10 weeks
1 mL x 10 mM (in DMSO)	$418	5 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Saredutant is an antagonist of selective NK2 receptors.
In vivo	Saredutant has dose-dependent effects on swim test immobility, with a low dose of 1 mg/kg having no effect and the doses of 3 and 10 mg/kg significantly reducing immobility. Saredutant has both antidepressant-like effects and synergizes with desipramine in an animal model of depression [1].
Alias	SR 48968C, SR 48968

Chemical Properties

Molecular Weight	552.53
Formula	C₃₁H₃₅Cl₂N₃O₂
Cas No.	142001-63-6
Relative Density.	1.26 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 250 mg/mL (452.46 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8099 mL	9.0493 mL	18.0986 mL	90.4928 mL
5 mM	0.3620 mL	1.8099 mL	3.6197 mL	18.0986 mL
10 mM	0.1810 mL	0.9049 mL	1.8099 mL	9.0493 mL
20 mM	0.0905 mL	0.4525 mL	0.9049 mL	4.5246 mL
50 mM	0.0362 mL	0.1810 mL	0.3620 mL	1.8099 mL
100 mM	0.0181 mL	0.0905 mL	0.1810 mL	0.9049 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SR-48968SR48968SaredutantNK2