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SARS-CoV-2 nsp3-IN-2

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Catalog No. T60271Cas No. 2038858-11-4

SARS-CoV-2 nsp3-IN-2 is a SARS-CoV-2 nsp3 macrodomain (Mac1) inhibitor with an IC50 value of 180 μM and functions as an ADP-ribosylhydrolase critical for coronavirus replication and pathogenesis. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe useful for viral research[1].

SARS-CoV-2 nsp3-IN-2

SARS-CoV-2 nsp3-IN-2

😃Good
Catalog No. T60271Cas No. 2038858-11-4
SARS-CoV-2 nsp3-IN-2 is a SARS-CoV-2 nsp3 macrodomain (Mac1) inhibitor with an IC50 value of 180 μM and functions as an ADP-ribosylhydrolase critical for coronavirus replication and pathogenesis. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe useful for viral research[1].
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
SARS-CoV-2 nsp3-IN-2 is a SARS-CoV-2 nsp3 macrodomain (Mac1) inhibitor with an IC50 value of 180 μM and functions as an ADP-ribosylhydrolase critical for coronavirus replication and pathogenesis. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe useful for viral research[1].
In vitro
SARS-CoV-2 nsp3-IN-2 exhibits weak potency against Mac1 in an ADP-ribose binding AlphaScreen assay, with an IC50 value of 180 μM [1].
Chemical Properties
Molecular Weight220.23
FormulaC10H12N4O2
Cas No.2038858-11-4
Storage & Solubility Information
StorageShipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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