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SDZ-MKS 492

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Catalog No. T12873Cas No. 114606-56-3
Alias MKS 492

SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.

SDZ-MKS 492

SDZ-MKS 492

😃Good
Catalog No. T12873Alias MKS 492Cas No. 114606-56-3
SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.
Pack SizePriceAvailabilityQuantity
5 mg$297 6-8 weeks
25 mg$987 6-8 weeks
50 mg$1,360 6-8 weeks
100 mg$1,860 6-8 weeks
1 mL x 10 mM (in DMSO)$365 6-8 weeks
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Product Introduction

Bioactivity
Description
SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.
AliasMKS 492
Chemical Properties
Molecular Weight433.46
FormulaC20H27N5O6
Cas No.114606-56-3
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 250 mg/mL (576.75 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3070 mL11.5351 mL23.0702 mL115.3509 mL
5 mM0.4614 mL2.3070 mL4.6140 mL23.0702 mL
10 mM0.2307 mL1.1535 mL2.3070 mL11.5351 mL
20 mM0.1154 mL0.5768 mL1.1535 mL5.7675 mL
50 mM0.0461 mL0.2307 mL0.4614 mL2.3070 mL
100 mM0.0231 mL0.1154 mL0.2307 mL1.1535 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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