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Semorinemab

Catalog No. T76886Cas No. 2159141-27-0

Semorinemab (RG 6100), an anti-Tau humanized IgG4 monoclonal antibody, selectively targets the N-terminal portion of the Tau protein, specifically amino acid residues 6-23. It exhibits a binding affinity to human Tau with a dissociation constant (Kd) of 3.8 nM. This compound is utilized in Alzheimer's Disease research [1].

Semorinemab

Semorinemab

Catalog No. T76886Cas No. 2159141-27-0
Semorinemab (RG 6100), an anti-Tau humanized IgG4 monoclonal antibody, selectively targets the N-terminal portion of the Tau protein, specifically amino acid residues 6-23. It exhibits a binding affinity to human Tau with a dissociation constant (Kd) of 3.8 nM. This compound is utilized in Alzheimer's Disease research [1].
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Bioactivity
Description
Semorinemab (RG 6100), an anti-Tau humanized IgG4 monoclonal antibody, selectively targets the N-terminal portion of the Tau protein, specifically amino acid residues 6-23. It exhibits a binding affinity to human Tau with a dissociation constant (Kd) of 3.8 nM. This compound is utilized in Alzheimer's Disease research [1].
Chemical Properties
Cas No.2159141-27-0
Storage & Solubility Information
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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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