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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $233 | 5 days | |
5 mg | $297 | 5 days | |
25 mg | $987 | 6-8 weeks | |
50 mg | $1,360 | 6-8 weeks | |
100 mg | $1,860 | 6-8 weeks |
Description | SGK1-IN-1 is a highly active and selective SGK-1 inhibitor with an IC50 of 1 nM. |
Targets&IC50 | SGK1:1 nM |
In vitro | SGK1-IN-1 (14n) demonstrates favorable SGK isoform selectivity, exhibiting potent activity towards hSGK2 and moderate activity against hSGK3, with IC50 values of 1 and 41 nM at ATP concentrations of 10 μM and 50 μM, respectively. Additionally, it shows cellular efficacy by inducing SGK1-dependent phosphorylation of GSK3β in U2OS cells, achieving an activity level of 0.69 μM[2]. |
Molecular Weight | 418.83 |
Formula | C17H12ClFN6O2S |
Cas No. | 1279829-87-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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