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SHP2-IN-6 hydrochloride

Catalog No. T39641Cas No. 2169223-49-6
Alias SHP2-IN-6 hydrochloride

SHP2-IN-6 hydrochloride is a highly potent inhibitor of SHP2 with an IC50 of 25.8 nM.

SHP2-IN-6 hydrochloride
Other Forms of SHP2-IN-6 hydrochloride:
JAB-3068T396402169223-48-5
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SHP2-IN-6 hydrochloride

Catalog No. T39641Alias SHP2-IN-6 hydrochlorideCas No. 2169223-49-6
SHP2-IN-6 hydrochloride is a highly potent inhibitor of SHP2 with an IC50 of 25.8 nM.
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Product Introduction

Bioactivity
Description
SHP2-IN-6 hydrochloride is a highly potent inhibitor of SHP2 with an IC50 of 25.8 nM.
In vitro
SHP2-IN-6 inhibits the proliferation of KYSE-520 cells with an IC 50 of 2.17 μM[1].
AliasSHP2-IN-6 hydrochloride
Chemical Properties
Molecular Weight513.0
FormulaC22H27ClF2N6O2S
Cas No.2169223-49-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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Keywords

SHP-2-IN-6 hydrochlorideSHP2-IN-6 HydrochlorideSHP2IN6 hydrochlorideSHP2 IN 6 hydrochloride
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