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SKF-82958 hydrobromide

Name: SKF-82958 hydrobromide
Brand: TargetMol
SKU: T16892
Rating: 4.5 (1 reviews)

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Catalog No. T16892Cas No. 74115-01-8

Alias Chloro-APB hydrobromide, (±)-SKF 82958 hydrobromide

SKF-82958 hydrobromide is a D1/D5 receptor full agonist.

SKF-82958 hydrobromide

😃Good

Catalog No. T16892Alias Chloro-APB hydrobromide, (±)-SKF 82958 hydrobromideCas No. 74115-01-8

SKF-82958 hydrobromide is a D1/D5 receptor full agonist.

Pack Size	Price	Availability	Quantity
2 mg	$71	5 days

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Product Introduction

Bioactivity

Description	SKF-82958 hydrobromide is a D1/D5 receptor full agonist.
In vitro	Neuropeptide and immediate early gene expression in striatonigral neurons of the normotensive striatum is induced by mixed D1 receptor SKF-82958, which induces behavioral activity and preprodynorphin (PPD) and substance P (SP) gene expression in medium spiny neurons in the dorsal, and especially, in the ventral striatum.
In vivo	Quantitative in situ hybridization was used to examine the contribution of muscarinic receptors to the transsynaptic regulation of striatal gene expression induced by D1receptor activation. The acute injection of the full D1 agonist, SKF-82958, would induce PPD, SP, and PPE mRNA expression in the intact rat striatum.
Alias	Chloro-APB hydrobromide, (±)-SKF 82958 hydrobromide

Chemical Properties

Molecular Weight	410.73
Formula	C₁₉H₂₁BrClNO₂
Cas No.	74115-01-8
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 102.5 mg/mL (249.56 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4347 mL	12.1734 mL	24.3469 mL	121.7345 mL
5 mM	0.4869 mL	2.4347 mL	4.8694 mL	24.3469 mL
10 mM	0.2435 mL	1.2173 mL	2.4347 mL	12.1734 mL
20 mM	0.1217 mL	0.6087 mL	1.2173 mL	6.0867 mL
50 mM	0.0487 mL	0.2435 mL	0.4869 mL	2.4347 mL
100 mM	0.0243 mL	0.1217 mL	0.2435 mL	1.2173 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SKF82958 HydrobromideSKF 82958 hydrobromideChloro-APB HydrobromideSKF-82958 HydrobromideSKF82958 hydrobromideSKF 82958 Hydrobromide