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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,970 | 8-10 weeks | |
50 mg | $2,580 | 8-10 weeks | |
100 mg | $3,400 | 8-10 weeks |
Description | SM-1295 serves as an antagonist to the inhibitor of apoptosis protein (IAP), demonstrating dissociation constant (Kd) values of 3077 nM for XIAP-BIR3, 3.2 nM for c-IAP1-BIR3, and 9.5 nM for c-IAP2-BIR3, respectively[1][2]. |
In vitro | SM-1295 (compound 5) binds to both cIAP1 and cIAP2 proteins, displaying a 900-fold higher affinity for cIAP1 over XIAP[1]. It exhibits an IC50 of 46 nM in MDA-MB-231[1]. |
Molecular Weight | 598.53 |
Formula | C29H36BrN5O4 |
Cas No. | 1562375-46-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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