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SOS1-IN-14

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Catalog No. T63887Cas No. 2793405-20-4

SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM). sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutated cancers and is more effective in tumour suppression than BI-3406.

SOS1-IN-14

SOS1-IN-14

😃Good
Catalog No. T63887Cas No. 2793405-20-4
SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM). sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutated cancers and is more effective in tumour suppression than BI-3406.
Pack SizePriceAvailabilityQuantity
25 mg$1,9408-10 weeks
50 mg$2,5308-10 weeks
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Product Introduction

Bioactivity
Description
SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM). sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutated cancers and is more effective in tumour suppression than BI-3406.
Chemical Properties
Molecular Weight550.57
FormulaC29H29F3N6O2
Cas No.2793405-20-4
Storage & Solubility Information
StorageShipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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