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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,670 | 6-8 weeks | |
50 mg | $2,180 | 6-8 weeks | |
100 mg | $2,800 | 6-8 weeks |
Description | SSTR5 antagonist 2 is a highly potent, oral active and selective antagonist of somatostatin (receptor) subtype 5 (SSTR5),with potential to treat type 2 diabetes mellitus (T2DM). |
In vivo | Both total and active circulating incretin hormone GLP1 levels in mice at a dose of 10 mg/kg increased by SSTR5 antagonist 2 (10 mg/kg, orally) . SSTR5 antagonist 2 increases pancreatic insulin secretion as well as total and active GLP1 release, and demonstrates synergistic effects in combination with DPP4 inhibitors. |
Molecular Weight | 546.63 |
Formula | C32H35FN2O5 |
Cas No. | 1254730-81-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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