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Suffruticosol A

Catalog No. T81072Cas No. 220936-82-3

Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it partially boosts BDNF signaling and has neuromodulatory effects, leading to the restoration of memory and cognitive performance in a scopolamine-induced mouse model.

Suffruticosol A

Suffruticosol A

Catalog No. T81072Cas No. 220936-82-3
Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it partially boosts BDNF signaling and has neuromodulatory effects, leading to the restoration of memory and cognitive performance in a scopolamine-induced mouse model.
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Product Introduction

Bioactivity
Description
Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it partially boosts BDNF signaling and has neuromodulatory effects, leading to the restoration of memory and cognitive performance in a scopolamine-induced mouse model.
In vitro
Suffruticosol A (20 μM; 24 hours) restores cell viability and survival rates in human neuroblastoma SH-SY5Y cells relative to treatment with scopolamine (2 mM) [1].
In vivo
Suffruticosol A (4 or 15 ng, biweekly; injected into the third ventricle of the brain) can ameliorate neuronal effects on cognition and memory impairments in a mouse model induced by scopolamine (1.0 mg/kg; intraperitoneal injection) [1].
Chemical Properties
Molecular Weight680.7
FormulaC42H32O9
Cas No.220936-82-3
Storage & Solubility Information
StorageShipping with blue ice.

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