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SZ-015268

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Catalog No. T63383Cas No. 2654003-68-4

SZ-015268 is a CDK7 inhibitor (IC50: 23.56 nM) that inhibits the proliferation of HCC70 (IC50: 33 nM), OVCAR-3 (IC50: 80.56 nM), HCT116 (IC50: 12.53 nM), and HCC1806 (IC50: 61.55 nM) cells, exhibiting a highly significant anti-tumor effect.

SZ-015268

SZ-015268

😃Good
Catalog No. T63383Cas No. 2654003-68-4
SZ-015268 is a CDK7 inhibitor (IC50: 23.56 nM) that inhibits the proliferation of HCC70 (IC50: 33 nM), OVCAR-3 (IC50: 80.56 nM), HCT116 (IC50: 12.53 nM), and HCC1806 (IC50: 61.55 nM) cells, exhibiting a highly significant anti-tumor effect.
Pack SizePriceAvailabilityQuantity
25 mg1.444 €8-10 weeks
50 mg1.881 €8-10 weeks
100 mg2.375 €8-10 weeks
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Product Introduction

Bioactivity
Description
SZ-015268 is a CDK7 inhibitor (IC50: 23.56 nM) that inhibits the proliferation of HCC70 (IC50: 33 nM), OVCAR-3 (IC50: 80.56 nM), HCT116 (IC50: 12.53 nM), and HCC1806 (IC50: 61.55 nM) cells, exhibiting a highly significant anti-tumor effect.
Chemical Properties
Molecular Weight498.62
FormulaC25H38N8O3
Cas No.2654003-68-4
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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