Tauro-Obeticholic Acid sodium

Name: Tauro-Obeticholic Acid sodium
Brand: TargetMol
SKU: T83858
Price: 50 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid. This compound undergoes taurine conjugation in the liver to form from obeticholic acid and can be reconverted to its original form by intestinal microflora.

Catalog No. T83858Cas No. 2278141-79-8

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Tauro-Obeticholic Acid sodium

Catalog No. T83858Cas No. 2278141-79-8

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Pack Size	Price	Availability	Quantity
1 mg	$397	35 days
5 mg	$1,620	35 days

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Product Introduction

Bioactivity

Description	Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid. This compound undergoes taurine conjugation in the liver to form from obeticholic acid and can be reconverted to its original form by intestinal microflora.
Alias	Tauro-6-Ethylchenodeoxycholic Acid, Tauro-6-Ethyl-CDCA, Obeticholic Acid Taurine Conjugate, Tauro-OCA, T-ECDCA

Chemical Properties

Molecular Weight	549.74
Formula	C₂₈H₄₈NO₆S.Na
Cas No.	2278141-79-8

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	Ethanol: 20 mg/ml PBS pH 7.2: 2 mg/ml DMSO: 20 mg/ml DMF: 20 mg/ml

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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