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Tauro-Obeticholic Acid sodium

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Catalog No. T83858Cas No. 2278141-79-8
Alias T-ECDCA, Tauro-OCA, Tauro-6-Ethylchenodeoxycholic Acid, Tauro-6-Ethyl-CDCA, Obeticholic Acid Taurine Conjugate

Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid. This compound undergoes taurine conjugation in the liver to form from obeticholic acid and can be reconverted to its original form by intestinal microflora.

Tauro-Obeticholic Acid sodium
Other Forms of Tauro-Obeticholic Acid sodium:
Tauro-Obeticholic acidT13092863239-61-6
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Tauro-Obeticholic Acid sodium

😃Good
Catalog No. T83858Alias T-ECDCA, Tauro-OCA, Tauro-6-Ethylchenodeoxycholic Acid, Tauro-6-Ethyl-CDCA, Obeticholic Acid Taurine ConjugateCas No. 2278141-79-8
Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid. This compound undergoes taurine conjugation in the liver to form from obeticholic acid and can be reconverted to its original form by intestinal microflora.
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1 mgInquiry35 days
5 mgInquiry35 days
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Product Introduction

Bioactivity
Description
Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid. This compound undergoes taurine conjugation in the liver to form from obeticholic acid and can be reconverted to its original form by intestinal microflora.
AliasT-ECDCA, Tauro-OCA, Tauro-6-Ethylchenodeoxycholic Acid, Tauro-6-Ethyl-CDCA, Obeticholic Acid Taurine Conjugate
Chemical Properties
Molecular Weight549.74
FormulaC28H48NO6S.Na
Cas No.2278141-79-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 20 mg/mL (36.38 mM), Sonication is recommended.
PBS pH 7.2: 2 mg/mL (3.64 mM), Sonication is recommended.
DMSO: 20 mg/mL (36.38 mM), Sonication is recommended.
DMF: 20 mg/mL (36.38 mM), Sonication is recommended.
Solution Preparation Table
PBS pH 7.2/Ethanol/DMSO/DMF
1mg5mg10mg50mg
1 mM1.8190 mL9.0952 mL18.1904 mL90.9521 mL
Ethanol/DMSO/DMF
1mg5mg10mg50mg
5 mM0.3638 mL1.8190 mL3.6381 mL18.1904 mL
10 mM0.1819 mL0.9095 mL1.8190 mL9.0952 mL
20 mM0.0910 mL0.4548 mL0.9095 mL4.5476 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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