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TAXUSIN
🥰Excellent
Catalog No. TN6763Cas No. 19605-80-2
TAXUSIN is a natural product of the yew tree and has certain anticancer and analgesic activities.
TAXUSIN
🥰Excellent
Purity: 99.7%
Catalog No. TN6763Cas No. 19605-80-2
TAXUSIN is a natural product of the yew tree and has certain anticancer and analgesic activities.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 475 € | In Stock | |
| 5 mg | 1.054 € | In Stock | |
| 10 mg | 1.624 € | In Stock |
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Purity:99.7%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | TAXUSIN is a natural product of the yew tree and has certain anticancer and analgesic activities. |
| In vitro | METHODS: Taxusin and verapamil (0.1/1/10μg/mL) were used to determine the accumulation of vincristine (VCR) in multi-drug-resistant human ovarian cancer 2780AD cells. RESULTS Taxusin's activity against VCR accumulation in multidrug-resistant tumor cells was approximately 1.5 times that of microverapamil. [1] |
| In vivo | METHODS: Taxusin was administered to mice at 30 mg/kg by intraperitoneal injection to treat the painful effect of abdominal contraction caused by p-benzoquinone. RESULTS Taxusin exhibited significant analgesic effects on abdominal contractions induced by p-benzoquinone. |
| Molecular Weight | 504.61 |
| Formula | C28H40O8 |
| Cas No. | 19605-80-2 |
| Smiles | C[C@]12[C@@H](OC(C)=O)[C@H](OC(C)=O)C=3C(C)(C)[C@](C[C@@]1(C(=C)[C@@H](OC(C)=O)CC2)[H])(C[C@H](OC(C)=O)C3C)[H] |
| Relative Density. | 1.16 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 6.25 mg/mL (12.39 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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