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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | TCO-PEG3-amide-C3-triethoxysilane is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1]. |
In vitro | PROTACs contain two distinct ligands connected by a linker: one binds to an E3 ubiquitin ligase and the other to the target protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 576.803 |
Formula | C27H52N2O9Si |
Cas No. | 2250217-32-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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