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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | TCO-PEG4-TCO is a PEG-based linker used in PROTACs that connects two ligands critical for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other binds to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [PROTACs]. |
Molecular Weight | 540.698 |
Formula | C28H48N2O8 |
Cas No. | 2243569-23-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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