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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $115 | Backorder | |
10 mg | $171 | Backorder | |
50 mg | $487 | Backorder |
Description | Tedizolid HCl is a reversible, novel oxazolidinone antibiotic (IC50: for MAO-A (monoamine oxidase-A), 8.7 uM; for MAO-B, 5.7 uM). It is the first oxazolidinone to be approved since linezolid in 2000. Tedizolid phosphate is the second commercially availabl |
In vitro | In vitro, tedizolid was a reversible inhibitor for both human MAO-A and MAO-B; for MAO-A, the value of IC50 was 8.7 uM, and for MAO-B, the value of IC50 was 5.7 uM. For these two inhibitions, add 46.0 and 2.1 uM of linezolid, respectively would be better [2]. |
In vivo | In vivo: It exhibited not only a potent activity against Gram-positive pathogens but also maintained activity against linezolid resistant bacteria. In the murine serotonergic model, the number of head twitches was analyzed after tedizolid phosphate was administrated by intraperitoneal injection [2]. |
Alias | Tedizolid HCl |
Molecular Weight | 406.8 |
Formula | C17H16ClFN6O3 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: > 13.57 mg/mL |
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