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tetranor-PGAM

Name: tetranor-PGAM
Brand: TargetMol
SKU: T38305
Rating: 4.5 (1 reviews)

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Catalog No. T38305Cas No. 52510-53-9

Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.

tetranor-PGAM

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Catalog No. T38305Cas No. 52510-53-9

Pack Size	Price	Availability
25 μg	Inquiry	35 days
50 μg	Inquiry	35 days
100 μg	Inquiry	35 days

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	310.346
Formula	C₁₆H₂₂O₆
Cas No.	52510-53-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

PBS (pH 7.2): 1 mg/mL (3.22 mM), Sonication is recommended.

DMSO: 50 mg/mL (161.11 mM), Sonication is recommended.

Ethanol: 50 mg/mL (161.11 mM), Sonication is recommended.

DMF: 50 mg/mL (161.11 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	3.2222 mL	16.1111 mL	32.2221 mL	161.1105 mL

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
5 mM	0.6444 mL	3.2222 mL	6.4444 mL	32.2221 mL
10 mM	0.3222 mL	1.6111 mL	3.2222 mL	16.1111 mL
20 mM	0.1611 mL	0.8056 mL	1.6111 mL	8.0555 mL
50 mM	0.0644 mL	0.3222 mL	0.6444 mL	3.2222 mL
100 mM	0.0322 mL	0.1611 mL	0.3222 mL	1.6111 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

tetranorPGAMtetranor-PGAMtetranor PGAM