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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $490 | 35 days |
Description | Thalidomide-O-C2-acid, designed by synthesizing an E3 ligase ligand-linker conjugate, comprises a cereblon ligand derived from Thalidomide and a linker commonly used in PROTAC technology. |
In vitro | PROTACs consist of two distinct ligands joined by a linker; one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Alias | Thalidomide-O-C2-acid |
Molecular Weight | 346.2916 |
Formula | C16H14N2O7 |
Cas No. | 2369068-42-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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