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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $784 | 35 days |
Description | Thalidomide-O-C4-COOH is a synthetic conjugate compound, serving as an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide and a linker utilized in PROTAC technology. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Alias | Thalidomide-O-C4-COOH |
Molecular Weight | 374.3447 |
Formula | C18H18N2O7 |
Cas No. | 2169266-67-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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