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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Thiol-PEG12-alcohol is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras], connecting two essential ligands necessary for PROTAC molecule formation and facilitating selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked together: one targets an E3 ubiquitin ligase, and the other binds to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | HS-PEG12-OH |
Molecular Weight | 562.71 |
Formula | C24H50O12S |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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