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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | THP-PEG8-OH is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, composed of two distinct ligands joined by a linker—one targeting an E3 ubiquitin ligase and the other targeting the desired protein—leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 454.55 |
Formula | C21H42O10 |
Cas No. | 658858-65-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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