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Thymidine-5'-O-(α,β-methylene)diphosphate sodium

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Catalog No. T83821Cas No. 71370-60-0
Alias α,β-MTDP, α,β-Methylenethymidine diphosphate, TMP-CP, Thymidine-5'-O-methylenediphosphate

Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM). It serves as a precursor in the synthesis of α,β-methylene-2’-deoxythymidine 5’-triphosphate, which is a non-cleavable substrate for DNA polymerase.

Thymidine-5'-O-(α,β-methylene)diphosphate sodium

Thymidine-5'-O-(α,β-methylene)diphosphate sodium

😃Good
Catalog No. T83821Alias α,β-MTDP, α,β-Methylenethymidine diphosphate, TMP-CP, Thymidine-5'-O-methylenediphosphateCas No. 71370-60-0
Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM). It serves as a precursor in the synthesis of α,β-methylene-2’-deoxythymidine 5’-triphosphate, which is a non-cleavable substrate for DNA polymerase.
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Product Introduction

Bioactivity
Description
Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM). It serves as a precursor in the synthesis of α,β-methylene-2’-deoxythymidine 5’-triphosphate, which is a non-cleavable substrate for DNA polymerase.
Aliasα,β-MTDP, α,β-Methylenethymidine diphosphate, TMP-CP, Thymidine-5'-O-methylenediphosphate
Chemical Properties
Molecular Weight466.16
FormulaC11H15N2O10P2.3Na
Cas No.71370-60-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: Soluble

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