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Tiodazosin

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Catalog No. T13162Cas No. 66969-81-1
Alias BL-5111

Tiodazosin is a competitive antagonist of the postsynaptic alpha-adrenergic receptor.

Tiodazosin

Tiodazosin

😃Good
Catalog No. T13162Alias BL-5111Cas No. 66969-81-1
Tiodazosin is a competitive antagonist of the postsynaptic alpha-adrenergic receptor.
Pack SizePriceAvailabilityQuantity
25 mg1.444 €6-8 weeks
50 mg1.881 €6-8 weeks
100 mg2.375 €6-8 weeks
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Product Introduction

Bioactivity
Description
Tiodazosin is a competitive antagonist of the postsynaptic alpha-adrenergic receptor.
In vitro
Tiodazosin acts as a potent competitive antagonist of postsynaptic alpha adrenergic receptors, effectively shifting the norepinephrine concentration response curves rightward in the mesenteric artery. Analysis using a Schild plot with two Tiodazosin concentrations yields a pA2 value of 8.66 and a slope of -0.99. Furthermore, Tiodazosin blocks norepinephrine-induced contraction in the portal vein, leading to a nonparallel suppression of the norepinephrine concentration-response curve and significantly reducing the maximal response to norepinephrine.
AliasBL-5111
Chemical Properties
Molecular Weight431.47
FormulaC18H21N7O4S
Cas No.66969-81-1
Relative Density.1.5g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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