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Tipiracil

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Catalog No. T60343Cas No. 183204-74-2

Tipiracil is an inhibitor of thymidine phosphorylase(TPase).

Tipiracil
Other Forms of Tipiracil:
Tipiracil hydrochlorideT2366183204-72-0
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Tipiracil

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Catalog No. T60343Cas No. 183204-74-2
Tipiracil is an inhibitor of thymidine phosphorylase(TPase).
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2 mg$595 days
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Product Introduction

Bioactivity
Description
Tipiracil is an inhibitor of thymidine phosphorylase(TPase).
In vitro
Tipiracil functions as a thymidine phosphorylase inhibitor, enhancing trifluridine's efficacy by impeding its metabolism via thymidine phosphorylase. This synergistic action facilitates the use of the Trifluridine-Tipiracil combination as an innovative oral treatment for metastatic colorectal cancer [2]. Additionally, Tipiracil fortifies the stability of FTD by mitigating its first-pass degradation through its inhibitory action on thymidine phosphorylase [3].
Chemical Properties
Molecular Weight242.66
FormulaC9H11ClN4O2
Cas No.183204-74-2
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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