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TL4830031

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Catalog No. T74864Cas No. 2084107-15-1

TL4830031 (compound 8i), a derivative of quinolone antibiotics, serves as a potent Axl inhibitor, displaying an IC50 value of 26 nM. It effectively inhibits the phosphorylation of Axl, as well as cell invasion and migration, showcasing its potential utility in cancer research [1].

TL4830031

TL4830031

😃Good
Catalog No. T74864Cas No. 2084107-15-1
TL4830031 (compound 8i), a derivative of quinolone antibiotics, serves as a potent Axl inhibitor, displaying an IC50 value of 26 nM. It effectively inhibits the phosphorylation of Axl, as well as cell invasion and migration, showcasing its potential utility in cancer research [1].
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Product Introduction

Bioactivity
Description
TL4830031 (compound 8i), a derivative of quinolone antibiotics, serves as a potent Axl inhibitor, displaying an IC50 value of 26 nM. It effectively inhibits the phosphorylation of Axl, as well as cell invasion and migration, showcasing its potential utility in cancer research [1].
Chemical Properties
Molecular Weight657.66
FormulaC35H33F2N5O6
Cas No.2084107-15-1
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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