Shopping Cart
- Remove All
- Your shopping cart is currently empty
TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of 27 nM for human TLR7 (hTLR7) and 12 nM for human TLR8 (hTLR8). This compound enhances the efficacy of PD-1/PD-L1 inhibitors in antitumor activity [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | 1.871 € | 8-10 weeks | |
50 mg | 2.451 € | 8-10 weeks | |
100 mg | 3.230 € | 8-10 weeks |
Description | TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of 27 nM for human TLR7 (hTLR7) and 12 nM for human TLR8 (hTLR8). This compound enhances the efficacy of PD-1/PD-L1 inhibitors in antitumor activity [1]. |
Targets&IC50 | TLR7:27 nM (EC50), TLR8:12 nM (EC50) |
Molecular Weight | 418.53 |
Formula | C24H30N6O |
Cas No. | 2649170-16-9 |
Storage | Shipping with blue ice. |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.