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Tos-PEG3-CH2COOtBu is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $42 | 7-10 days | |
100 mg | Inquiry | 7-10 days | |
200 mg | Inquiry | 7-10 days |
Description | Tos-PEG3-CH2COOtBu is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked together: one targeting an E3 ubiquitin ligase and the other a target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | Tos-PEG3-CH2COOtBu |
Molecular Weight | 418.5 |
Formula | C19H30O8S |
Cas No. | 1530778-24-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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