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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Tos-PEG5-CH2COOtBu is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked together; one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 506.61 |
Formula | C23H38O10S |
Cas No. | 1949793-62-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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