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Tos-PEG6-OH, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Tos-PEG6-OH, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked by a connector: one binds to an E3 ubiquitin ligase, while the other targets a specific protein. Utilizing the ubiquitin-proteasome system within cells, PROTACs enable the selective degradation of target proteins[1]. |
Molecular Weight | 436.52 |
Formula | C19H32O9S |
Cas No. | 42749-28-0 |
Relative Density. | 1.196 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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